Water Is Under Threat Of Being Exhausted Environmental Sciences Essay

Like most natural resources, drinkable H2O is under menace of being exhausted due to over-consumption. And like most natural resources, one time depleted, regeneration of the land H2O and surface H2O will take 100s of old ages. At the present rate of ingestion every chance needs to be utilized to conserve our beginnings of H2O and create statute law that will promote wise usage of H2O. Governmental bureaus and private endeavor should mobilise their resources to construct proper substructure for H2O preservation like edifice dikes, reaping rain H2O, etc. This paper is a survey of current and future tendencies with regard to H2O use, and will show a image of what the following twosome of decennaries might look like. Water Technology and Emerging Tendencies: 1. Governments of all states are coping with issues related to supplying safe imbibing H2O to its citizens. In position of the pressing demand extended research has been done and some new engineerings and procedures have emerged. Electrolyzing imbibing H2O is efficient in extinguishing water-borne sources. E-water is formed by go throughing an electrical current to a weak solution of salt and H2O, which turns super- acidic that kills the pathogens. Water is therefore sanitized for imbibing intents and does n't look, odor, or taste any different from tap H2O ( Zinzi 2010 ) . In the hereafter scenario this will be a major agencies of recycling used H2O to do it drinkable and suited for ingestion. 2. Another technological promotion that has come to visible radiation is the usage of aquaporins as biomimetic membranes to let transition of lone H2O molecules and nil else through it. No molecule that is larger or smaller than a H2O molecule can go through through the channel. This ensures that drosss are blocked from polluting the H2O. The lone disadvantage of commercializing biomimetic membrane is to do it strong and stable plenty to defy repeated fouling and cleansing procedures. In future this will turn out to be a pillar in recycling waste H2O and saline H2O to do them drinkable for human ingestion. Politicss, policy and statute law: 1. Harmonizing to the US Geological Survey, future H2O demands can non be accurately identified, but tendencies of increasing emphasis on H2O resources the universe over can be widely recognized. Even though the jobs can be recognized, they will non be resolved on their ain. For case, aquifers can non be recharged rapidly after they are over-pumped. Water allotment struggles have been observed in many parts, these jobs are compounded by increasing population and forseeable drouths. Governmental bureaus like the geological study or similar bureaus are in a place to help states in apprehension, predicting, and minimising the impact of these crises. 2. The job of H2O handiness becomes more serious and outstanding as the explosive growing of population is predicted globally ( For e.g.US Census Bureau undertakings the US population to increase about 50 % from 282 million in 2000 to 420 million in 2050 ) . The hydrological agenda of any part is mostly influenced by regional factors like clime, rainfall etc. Infrastructure including waste H2O aggregation, storage and distribution of H2O, agribusiness, electric power coevals ; building of roads and commercial edifices and clean imbibing H2O for residential countries, must be planned for the sustainability of H2O. The job of worsening surface H2O and land H2O resources are a cause for concern. Consumption: 1. Projecting the information for 2026, based on the current tendencies of the economic demand for commercial and residential H2O use, it can be estimated that the engineering affecting optical maser beams used as a big scale H2O purification procedure. This technique involves laser beams being pointed at a watercourse of imbibing H2O that can observe and take unsafe pathogens and sublimate H2O for imbibing intents. This engineering will be used to supervise H2O safety for both domestic and industrial usage ( Zinzi 2010 ) . Giant strides in the development of cost effectual ways of reaping rain H2O will be made to prolong agribusiness and gardening. 2. Industrial H2O is likely to be higher in developing states compared to developed states. However, the overall industrial H2O ingestion will diminish globally due to betterments in H2O preservation engineering and monitoring of demand and execution of Governmental ordinances. Demand for H2O used for irrigation will, similarly, addition in the development states and is projected to be the most intense in sub- Saharan Africa and the Latin American states followed by Western Asia. Water scarceness in these parts may be intense as existent demand is frequently higher than projected demand. As a consequence the planetary harvest output rate may worsen ( Rosegrant, Ximing & A ; Cline 2002 ) . Families and relationships: 1. In order to project the demand for municipal and domestic H2O for 2026 one needs to analyze and acknowledge, cipher the jutting demand and put precedences for all bing and possible H2O use. Projection of future demands for municipal H2O depends on the alteration in the economic construction of a part and the efficiency of implementing alternate H2O usage policies. Other factors that may lend to an accurate projection include household size, distribution of household units between unitary and joint households and per-capita H2O usage ( Willsie & A ; Ratt 1974 ) . Water will go more of a trade good and ingestion will depend on the purchasing capacity of single users. 2. Future H2O demands may be computed on the footing of figure of individual and multi-family units, addition in population and the gross per capita usage of H2O per part. Domestic H2O usage depends on the size of the family and the seasonal usage of H2O. Education and consciousness degrees with respect to minimising wastage of H2O are besides of import factors. In 2026, H2O rationing will depend on the economic position and size of belongings in urban countries. ( House-Peters, Pratt & A ; Chang 2010 ) . Sharing of H2O resources across international boundary lines will be in focal point as struggles may originate due to unequal allotment and general scarceness of H2O. Health and fittingness: 1. Human organic structure is made up of 75 % H2O ( Maxx 2009 ) and we need to imbibe H2O in order to remain alive. Water is necessary for the proper operation of variety meats like the encephalon, liver and kidneys. Without H2O our organic structures will acquire dehydrated and will be afflicted with serious unwellnesss. So in order to remain fit and healthy all living existences need to devour big measures of H2O. Water is considered to be the wonder drug by many. Due to scarceness of drinkable H2O, people will be given to happen replacements in the signifier of soft drinks, milk merchandises and caffeine. 2. At the present rate of ingestion, the demand for H2O will far transcend the supply of H2O which will take to a H2O pricing system in most states. Denationalization of H2O across the Earth will hold serious branchings every bit far as wellness and fittingness is concerned because poorer people will non be able to afford sufficient measures of imbibing H2O. This will take to dehydration related chronic diseases like allergic reactions, high blood pressure, diabetes, and unsusceptibility upsets. This will impact the wellness of the society as economically backward populations will non be able to afford medical specialties and governmental resources will be strained to supply wellness attention benefits. Work and leisure: 1. By 2026, people will be preoccupied with developing newer techniques in H2O direction ( Griffiths 2009 ) and H2O preservation. So this will supply employment to a big population and will include H2O recycling and transit. A batch of scientific work will be encouraged by authorities every bit good private establishments at national and international degrees. The handiness of H2O will ever stay as nature has its ain manner of recycling H2O, nevertheless, the rate of recycling H2O is lower than the rate at which H2O is being polluted and made unfit for ingestion. Building H2O canals, reservoirs and dikes will go a precedence with governmental bureaus and will supply chances for employment, particularly in developing states. 2. As developing states gain economic stableness and richness, demand for H2O for basic healthful demands will increase. More people will be able to afford comfortss like Jacuzzis, auto lavation, horticulture and swimming pools ( Griffiths 2009 ) . This will add to the H2O crisis in 2026. Depending on the richness degree, fewer people will be able to afford installations that we take for granted for illustration holding swimming pools at place and H2O Parkss, etc. Global heating will impact winter athleticss like skiing which will ensue in beaches and H2O athleticss around the sea going more popular as leisure activities. Biophysical environments: 1. Biophysical environment in relation to H2O trades with H2O ingestion by people, land and farm animal. The alterations in clime, peculiarly rainfall, have deductions for fresh fish resources as it has for agribusiness. Since the handiness of natural H2O is non uniformly distributed, transit of H2O to countries with high denseness of population will go common characteristic. Puting extended web of grapevines overland for H2O for human ingestion every bit good as for farm animal will affect considerable outgo. Water holes, pools and swamps will necessitate to be tapped to run into the demands of croping for cowss. Herding direction and land use will necessitate to be implemented ( deLeeuw 1993 ) . 2. Demographic alterations are anticipated in future depending on the ready handiness of H2O for domestic and livestock use. In parts where the cost of H2O transit can non be afforded, people will switch to countries closer to natural H2O beginnings. Heavy industries are most likely to be set up close to rivers and other natural H2O organic structures as this will minimise the cost of transporting H2O for industrial usage. Land use for agribusiness will Promising societal invention: New stuffs: De Leeuw, PN 1993, iThe survey country: Biophysical environmenti , FAO Corporate Document Repository viewed 13 September 2010 & lt ; hypertext transfer protocol: //www.fao.org/wairdocs/ILRI/x5552E/x5552e06.htm & gt ; Griffiths, J 2009, Water Facts and Trends, World Business Council for Sustainable Development, viewed 13 September 2010 & lt ; hypertext transfer protocol: //www.wbcsd.org/DocRoot/lD1tMGiLZ7NL9mBOL2aQ/WaterFactsAndTrends-Update.pdf & gt ; Haughn, S 2008, ‘Global Tendencies 2025: Water deficits threaten nutrient security, energy supply and geopolitical stableness ‘ , Circle of Blue, viewed 12 September 2010 & lt ; hypertext transfer protocol: //www.circleofblue.org/waternews/2008/world/africa/global-trends-2025-water-shortages-threaten-food-security-energy-supply-and-geopolitical-stability/ & gt ; House-Peters, L, Pratt, B and Chang, H 2010, iEffects of Urban Spatial Structure, Sociodemographics, and Climate on Residential Water Consumption in Hillsboro, Oregoni , JAWRA Journal of the American Water Resources Association, 46: 461i472, viewed 13 September 2010 hypertext transfer protocol: //onlinelibrary.wiley.com/doi/10.1111/j.1752-1688.2009.00415.x Kwok, SC, Lang, H & A ; O'Callaghan, P 2009, Water Technology Markets, Global Water Intelligence, viewed 12 September 2010, & lt ; hypertext transfer protocol: //www.globalwaterintel.com/client_media/uploaded/files/sample_water_tech_markets_aquaporins.pdf & gt ; Maxx, 2009, iWater- Natureis Wonder Drugi , How To Maximize Your Health And Fitness, viewed 12 September 2010 & lt ; hypertext transfer protocol: //health-and-fitness-buzz.blogspot.com/2009/05/water-natures-wonder-drug.html & gt ; Rosegrant, MW, Ximing, C & A ; Cline, SA 2002, Global Water Outlook to 2025, Colombo: International Water Management Institute, pp: 4-7, viewed 12 September 2010, Google Books. Willsie, RH & A ; Ratt, HL 1974, iWater Use Relationships and Projection Corresponding with Regional Growthi , Journal of the American Water Resources Association, 10: 360i371, viewed 13 September 2010 & lt ; hypertext transfer protocol: //onlinelibrary.wiley.com/doi/10.1111/j.1752-1688.1974.tb00575.x & gt ; Zinzi, F 2010, iTrends in Water Technology and Consumptioni , Ezine @ rticles, viewed 12 September 2010, & lt ; hypertext transfer protocol: //ezinearticles.com/ ? Trends-in-Water-Technology-and-Consumption & A ; id=4074865 & gt ;

Combining Vinegar and Baking Soda- Lab Report

The second trial displayed similar results of a weak presence of carbon dioxide. The solution bubbled up, the cork stayed stationary in the top of the bottle, but the solid did not dissolve completely. A third trial was performed in which we decided to increase the amount of vinegar used. The indicator which triggered this decision was the resulting solid at the bottom of vessel. In the third trial we kept the baking soda our constant at % TTS. ND deed 2 ounces of vinegar. The results remained similar to trial two. The solution bubbled, the cork remained stationary In the top of the bottle, and there remained solid In the bottom of the vessel. A fourth trial was performed In which we again Increased the amount of vinegar added to dissolve the solid. In the fourth trial we kept the baking soda our constant at % TTS. And added 3 ounces of vinegar. The results Improved slightly as we saw that, although the cork remained stationary, the solution bubbled substantially higher In the bottle displaying a stronger presence of arbor dioxide.It was also noted that the solid that remained was much less than In past trials. A fifth trial was performed in which we again increased the amount of vinegar added to dissolve the solid. In the fifth trial we kept the baking soda our constant at TTS. And added 4 ounces of vinegar. The results dramatically changed. The solution bubbled almost immediately and so quickly that the solution overflowed that there was more than enough baking soda, there may have been too much vinegar added and that the technique of the pour may have been too slow or the exults may have been different.A sixth and final trial was done in which we kept the baking soda our constant at % TTS. And reduced the amount of vinegar poured to approximately 3 h ounces. The pour was done more quickly and the bubbling reaction took place almost immediately. The cork was placed in the bottle after the overflowing had started to occur so the reaction of the cork popping st ill was not quite achieved, however the last trial did show a large amount of carbon dioxide present. The data from each trial is recorded in the table below on the following page.In order to study he reaction we created trials which would allow the chemicals to combine within a vessel. The movement or lack of movement from the cork allowed us to measure the amount of carbon dioxide present in each experiment. My results showed the trial with the greatest reaction was the final trial because the solution bubbled almost more than the other trials. If the cork had been placed inside of the bottle quicker or if the pour had been slightly slower the cork would have popped with stronger force.The trial with the least reaction was trial one because the solution bubbled the least wowing a weak presence of carbon dioxide, the solid dissolved completely and the cork remained completely stationary showing there was very little pressure within the vessel. While observing the experiment, I noti ced that the more vinegar added and the quicker the pour the greater the reaction and the more the solution bubbled. In order to further investigate the experiment, next time I would try the experiment utilizing only one student performing the pour to keep consistency of the control of the pour and the pressure being applied to the cork.

Blue Ocean Strategy

Blue ocean strategy is a book of business strategy by W. Chan Kim and Renà ©e Mauborgne. The blue ocean strategy explains how to move your business into new markets with less competition and greater profitability. The book is basically divided into three main parts. The first part covers some important concepts of blue ocean strategy such as value innovation, differentiation and low cost and key analytical tools and frameworks used in this strategy. The second part explains the four steps of blue ocean strategy formulation. The main idea behind this book is to present an organized framework for identifying and implementing out of the box and never been thought before blue ocean strategies. If one is capable of thinking out of the box, something other than a traditional strategy then it will enable us in formulating a blue ocean. The basic idea of blue ocean strategy is to reconstruct market boundaries to break from the competition and create blue oceans. The main idea behind consisted of two parts: first was to discover whether systematic patterns existed in reconstructing market boundaries and secondly whether r not these applied to all kinds of businesses and industry sectors. The researchers found six basic approaches also called six paths framework for reconstructing market boundaries. These six approaches challenge the traditional six assumptions involved in formulating strategies which lead to creating red oceans. They proceed by emphasizing on the fact that the companies should break out of these boundaries which they define by themselves on how to compete. Path One: Look across alternative industries The first path for a company is not only to compete with firms in its own industry but it should also consider the firms in alternative industries offering such products and services which have different functions and forms but serve the same purpose. One such example is that of Net Jets which came up with the idea of fractional jet ownership. Net Jets created a multi billion dollar Blue Ocean of private jets and commercial travel which offered low variable and fixed costs as compared to commercial airline travelling and thus it created a entirely new market and was the only  survivor and market leader of all the 57 new entrants. Similar example is that of NTT DoCoMo which broke out of Red Ocean of intense competition by breaking the tradeoff between the alternatives. Path Two: Look across different strategic groups within industries The second path given by Blue Ocean is to get out of the competition by looking across different strategic groups. In this context the different companies in an industry working on a similar strategy fall under one strategic group and others in different strategic groups. And in this highly intense and competitive market the key to creating a Blue Ocean across different strategic groups is to break out of these by creating a better understanding of the factors that determine customers’ decision to trade up or down from one group to another. A very good example given here is that of Curves which is a women fitness company, broke out of the completion by building on the advantages of both the traditional health clubs and the home exercise programs. Other examples are that of Ralph Lauren, Toyota Lexus, Sony Walkman and Champion Enterprises which created Blue Oceans by breaking out of their strategic groups by offering the advantages of both the strategic groups of their industries that resulted in their success. Path Three: Look across Chain of Buyers In most of the industries it has been a trend to target only a single type of buyer. However there is a chain of buyers which includes the purchasers, the actual users and some times also the influencers. Each of these three groups of buyers may seem similar to the seller but actually they are different as they provide different value. Conventionally different industries focus only on a single customer segment and think that they are the only possible target customers, however it is a wrong approach and they need to think out of the box which can lead to creating new Blue Oceans. Novo Nordisk a Danish insulin producing company created a Blue Ocean in the insulin industry. Previously Nordisk like all other pharmaceuticals focused only on doctors which are the influencers. But Novo Nordisk came up with the idea of Novo Pen which was easy to use and was targeted directly at the end users that is the diabetes patients. This helped them in creating a blue ocean and continuous improvement and advancement in their offering resulted in  maintaining their Blue Ocean success. Path Four: Look across complementary product and service offerings This path explains that the importance of complementary products and services should never be overlooked as the untapped value is often hidden in them. Providing the facilities of baby sitting and car parking are complementary to movie theatres. NABI made use of the fiberglass instead of steel body buses and had a huge impact on lowering the maintenance and other costs and created a Blue Ocean in the bus industry. Philips created the kettle with a mouth filter and Barns and Noble came up with knowledgeable staff in their lounging were such complementary products and service which were revolutionary. Path Five: Look across functional or emotional appeal to buyers There are different types of appealing strategies that are adopted by companies to appeal the customers. Some of these are functional while others are emotional. The different examples discussed in this case are the Cemex (Mexican Cement Company) and QB house (Japanese Barber shop) which created Blue Oceans by appealing their customers through different functional and emotional offerings. Path Six: Look across time This path illustrates that how important it is to have foresight and keep in mind the changes that are to take place with passage of time. This can be done by looking across the time in terms of the value a market delivers today to the value it may deliver tomorrow. Apple capitalized on the changing trend in the music industry and came up with ITunes music store for its IPod which also helped it in stopping illegal selling of music and creating a Blue Ocean. Cisco Systems also looked ahead of time and accounted for the growing demand of high speed data exchange with its routers, switches and other networking devices. 2. Focus on the Big Picture, Not the Numbers Traditionally what most of the strategies lack is that they don’t think out of the box and thus lack the view of the big picture and thus they key is to create a strategy canvas to arrive at a Blue Ocean. Drawing Your Strategy Canvas Drawing a strategy canvas has never been an easy to do job. It involves  identifying the key factors of competition which can be done by assessing that to what extent your company and its competitors offer the most competing factors and what are the actions that are being taken by you and your competitors. This process after the implementation of six step model involves steps in visualizing strategy which are as follows: Step One: Visual Awakening The process of visual awakening is very important to change the mind set of such people especially the executives who are resistant to change and like the status quo. However this problem can be overcome by asking such people to draw the value curve of their company’s strategy which will trigger the need for change in their minds and thus they will be inclined towards change and will come up with new and different strategies. Step Two: Visual Exploration The wakeup call was just the first step. The next step is to send team it to field, putting managers face to face with customers and experiencing by themselves what problems they have with their products and services and what are their perceptions. This task should not be outsourced as it is very important to see these things by your self rather than letting others do the work of your eyes. They should observe their customers (existing, lost and new ones) as well the customers of their competitors and then come back and analyze their strategies. Step Three: Visual Strategy fair In the third step of visualizing strategy the teams are asked to draw six new curves of strategy and create a compelling tagline which can emphasize the strategy in a better way. After that the teams are asked to present them and on the basis of feedback and discussion the new curves for strategy are formulated. Step Four: Visual Communication The last step is to communicate the newly formulated future strategy to employees in an easy and understandable manner. This can be done by distributing one pager showing old and the new strategies to the employees and then can be discussed with every one. 3. Reach beyond Existing Demand The third principle for creating Blue Ocean is to reach beyond the existing demand. This to increase the demand for a new offering and two strategies are followed by companies to achieve this goal. One is to focus on existing markets and customers and the other is to target finer markets or customer segments to accommodate buyer differences. Another important concept explained here is to maximize the size of Blue Ocean, which says that once the Blue Ocean has been created the next step is to maximize its size. For this purpose companies instead of focusing on their customers try to focus on the non-customers by taking the reverse approach which allows the companies to unlock mass of customers and demand which did not exist before. Callaway Golf is one such company which created demand for its offering by focusing on its non-customers. The Three Tiers of Non-Customers According to Blue Ocean strategy there are three different tiers of non-customers that can be converted in to customers which are as follows: i. The first tier of non-customers is closest to market sitting on its edge waiting to jump ship and shift to another industry as soon as the opportunity knocks. ii. The second tier is of customers who refuse to use you offerings. These are buyers who have used your industry offerings just as an option to fulfill their needs but have often voted against them. iii. The third tier is of non-customers who are farthest from your market and have never thought or considered of using you industry offerings as an option and can only be attracted by focusing on commonalities. 4. Get the Strategic Sequence Right The fourth principle of formulating the Blue Ocean strategy is to get the strategic sequence right. This principle focuses on building robust business models to ensure healthy profits based on Blue Ocean strategy.

KFC In India Essay Example | Topics and Well Written Essays - 3000 words

KFC In India - Essay Example Globalization is a process of interaction and integration among the people, companies, and governments of different nations, a process driven by international trade and investment and aided by information technology. This process has effects on the environment, on culture, on political systems, on economic development and prosperity, and on human physical well-being in societies around the world. (Website: http://www.globalization101.org/What_is_Globalization.html Globalization makes use of modern technological advancements and also focuses on the quick transfer of technology, to keep with the changing world. Therefore, Globalization is a phenomenon that charges towards progress and engulfs the whole world, in this process. The development in technology has led to the process of Cloning and other artificial forms of life. Today, we have hybrid varieties of fruits and vegetables being imported from various parts of the world; which truly symbolises globalization. The widespread Globalization has led to the free movement and transfer of goods, capital, technology and people, from one hemisphere to the other. Therefore, there is an influx of numerous commodities across the globe. One of the entrants in the last decade, into the Indian market, is the KFC chain. The entry has been welcomed with both, expectations and controversy. Kentucky Fried Chicken, popularly known as KFC made its entry into India in 1995, by setting up an outlet in Bangalore. This was the time when the Indian market w as opening up to the international one, with MNCs and other international organizations coming into play. This was also the time when KFC was in the expansion mode and found the Indian market ideal to target. While the operations flagged off with success, KFC has come under the hammer for a few reasons. Firstly, it was the high level of monosodium glutamate content present in the food served. The high levels of the MSG content, in fact, were about three times higher than the prescribed limit. Next, the PETA or the People For Ethical Treatment of Animals organisation had problems with the manner in which the KFC processed its food and used animal livestock. In addition to this, farmers from the Karnataka Rajya Ryota Sangha (KRRS) landed at the doorstep of the first Bangalore outlet, to protest against the expansion of the fast-food joint into India. This paper attempts to analyse the entry of KFC into India, the problems that have been leveled against it and the various protests and the ethical implications associated. REASONS FOR PROTESTS The KFC chain has been subject to protests from a number of quarters. On the very first day, farmers marched onto the restaurant opening and protested

Native American Tribes Case Study Example | Topics and Well Written Essays - 250 words

Native American Tribes - Case Study Example In addition, the reason why they are more competitive than fellow domestic firms in the cities is because â€Å"the rates of the rural outsourcers are better than their domestic counterparts in big cities because the towns and small cities where they operate have lower living costs† (Leiber, 2010). To date, the remaining Indian tribes present in Texas actually includes the Alabama-Coushatta Tribes of Texas (located in Livingston, Texas), the Kickapoo Traditional Tribes of Texas (located in Eagle Pass, Texas) and the Ysleta del Sur Pueblo (located in El Paso, Texas) (Texas.gov, n. d.). So far, both the Alabama-Coushatta and the Ysleta del Sur Pueblo tribes in Texas are not engaged in rural outsourcing activities (Alabama-Coushatta Tribes of Texas, n. d; Ysleta del Sur Pueblo, n. d.). Such is also the case for the Kickapoo Traditional Tribes of Texas: none of them are currently engaged in rural outsourcing (Kickapoo Traditional Tribes of Texas, n. d.). In fact, most of these tri bes are actually engaged not in outsourcing, but in the entertainment (specifically gambling and casino) industry (Ysleta del Sur Pueblo, n.

Business ethics Essay Example | Topics and Well Written Essays - 1750 words

Business ethics - Essay Example Business ethics Corporate responsibility entails two issues: doing the positive good to the community, and doing no harm or whatsoever to the community.This means that the corporations pay back to the community through participating in community beautification efforts and events, volunteering expertise, donating money to the worthy causes and being a responsible employer. On the other hand, doing no harm entails efforts of the business towards the environment in its production activities, transportation and disposal. Therefore, in order to best examine moral corporations and corporate responsibility for the environment let us start by considering issues of the environment we face (McLachlan, 2008). There is a wide possibility of developing a moral corporation; this requires looking closely at values and changing attitudes. This paper seeks to form a position for the development of a moral corporate culture and map out a specific plan for obtaining a moral corporation. Moral responsibility is the sta te of deserving moral praise, reward, blame, or punishment for an omission or act, with respect to moral obligations. Making decisions on whether or not something is obligatory morally is a concern of principles of ethics. Corporations with moral responsibility for actions are referred to as moral agents. Such corporations are able to reflect on their circumstances, make intentions concerning how they act, and finally do such actions. Developing a moral corporation is a free will issue whether or not corporations will be morally responsible for the actions they get involved in. The scholars’ debate over the attributes of moral responsibility in corporations has been going on for decades. The conformational approach to this argument is to determine the necessary conditions for moral corporations and plan for the development of moral corporations, and whether such conditions can be satisfied by corporations (McLachlan, 2008). The development of moral corporations needs to ensur e that the environment is duly protected. Environmental ethics iscomplicated in practice because of the numerous distinct perspectives that are involved. The development of moral corporations needs to encompass this ethics. In some situations it may be difficult for corporations to understand the environmentalists’ arguments on environmental ethics. Disagreements, hence, rise on plans for developing a moral corporation. It is obvious that corporations possess different viewpoints on ethics of the environment. It is, however, possible for corporations put their different options aside for the good of the environment and agree simply that some actions about the environment need to be done in order to make corporations morally upright. In order to develop a moral corporation, such corporations need to admit that protection of the environment is important, whether they are acting out of a sense of responsibility or out of a sense of self-preservation for the future generation, fo r to the Earth itself or to all the forms of life. Corporations need to adopt an environmental pragmatism. This ensures that moral corporations are developed and maintained; that the corporations can achieve a consensus on the values of the environment that identify and determine the policies of the environment that all other corporations can agree on (McLachlan, 2008). When thinking of moral corporations, a plethora of questions rise: if the consumerism was predated by an ethical community, then how did consumerism supersede the morals of business practitioners? How does it

Barbie Doll Advertisement Essay Example | Topics and Well Written Essays - 1250 words

Barbie Doll Advertisement - Essay Example The market segmentation and semiotic analysis of Barbie advertisement for pre-tween girls reveal that their advertisement is geared towards the dominant ideology which promotes the ideal image of female beauty and body type. In America, prior to 1959, most dolls were either infants or toddlers. The Barbie doll was the first adult doll toy. She was adopted from the German doll Bild Lilli. The creator of the Barbie doll, Handler, was inspired by her daughter, who was giving adult roles to paper dolls to create a doll with a mature body. The Barbie doll was named after Handler’s daughter Barbara. Since then Barbie dolls became very popular among girls. The toy market took advantage of a child’s desire for â€Å"the whole spectrum of character licensed products† (Coulter, 2014, p.417) and as a result, they created a license for character products, which allow Barbie’s doll image to appear on clothes, magazines, board games and later on online games. As Coulter (2014) notes, the market for children is divided into segments based on the age and gender of the child (p.417). The purpose of market segmentation in such categories as boys/girls, infants, babies, and toddlers is to sell more products. If a child uses the same toy without wanting a new one, then toy producers will have less profit. Therefore, the market is divided not just into gender, but also into age categories. For example, pre-tween boys are interested in Transformers and Hot Wheels, while girls are interested in Bratz and Barbie dolls. Younger boys are interested in Spiderman and girls are interested in Strawberry Shortcake. Market segmentation was created not only to understand the audiences and consumers but also to create a constant need for new products. Using the Barbie advertisement, illustrated on page 6, I will demonstrate how market segmentation works in practice.

Titian and Renaissance Research Paper Example | Topics and Well Written Essays - 1250 words

Titian and Renaissance - Research Paper Example Venetian reflection of color and a special atmosphere of Venetian style are combined with traditional Renaissance traditions. Titian works are full of emotions; even in his portraits we can see an intense emotional charge. Further on we will focus our attention on his two famous paintings: Portrait of Isabella d’Este and Christ and the Adulteress. These works signify common and different features of Titian paintings and those ones of Leonardo daVinci. We will try to underline common and different features between them, but of course, the main part of our attention concerns Titian paintings and the relevance of his style to the epoch of Renaissance. First of all, we should look for the features of aesthetic in his paintings. Moreover, there is a need to claim that the painter reflected ideally both humans and nature. He was looking for an ideal balance between the nature and the human world. An air of harmony is evident in the paintings of Titian. Christ and Adulteress This pai nting belongs to the High Renaissance period. The theme of adulteress is depicted in a dynamic nature by Titian. It is evident that this painting reflects a changeable and a controversial nature of this situation. We can see gorgeous clothes of the accused woman. This tendency we can also see in other paintings of the painter, because social status of the citizens of the Venetian society. It is very important to underline the contrast of the gorgeous clothes of Jesus Christ, the Adulteress and people around them. His background reflects nature from the remote perspective. We are enchanted by the green landscapes and there are blurred limits of the horizon and it is very interesting to consider the smallest details of the painting. Thus, Titian shows that he is much more concerned about the foreground of the painting (Christ and the Adulteress). The sea and green landscapes, which can be seen at the background of the painting, are of minimal concern for the painter. On the example of the vanishing line of green grass, we can see that the painter does not exactly draw a visible path between individuals, depicted on the painting. There is an evident opposition between the light and darkness of the painting. The building has dark edges and it is especially evident on the background a bright green color. The image of a woman is leaning her head and we can claim that this woman confessed all her mistakes and she seems to be blessed. We can compare this painting with the painting The Last Supper by Leonardo da Vinci. Emotions are reflected on the faces of people around the table. The same actions are depicted on the painting by Titian. People on the painting are fixed in their certain conditions and emotional states. Therefore, the painting by Titian is an emotionally-charged and rich in color creative work. Portrait of Isabella d’Este We can see an ideal woman. The image of this noble and wealthy woman has been depicted by numerous painters. Therefore, she wa s considered to be an ideal image of a woman during the period of Renaissance. We can claim that the background for this image and her depiction we can see in the works by Petrarch: she has blonde hair, fair skin, beautiful lips and cheeks, and almond-shaped blue-green eyes. Therefore, there was a well-accpeted tendency to depict noble women in the way they liked. They wanted to be ideals and idols of beauty for the painters. There are letters of Isabella d’Este, where she asks for making her portrait and appeals for Master Leonardo da Vinci.

The form of local government and his structure Essay

The form of local government and his structure - Essay Example Out of 39 counties of Washington, 33 are non-charter, which run the government of commission form offered by the state. Under the commission form, the county government is governed by a body that consists of three members of commissioner’s board who are elected. The election is based on partisan and serves as a legislative body of the county as well as performing executive functions. Counties with greater population of more than 300,000 can add the number of commission members from three to five. On the other hand, home rule charter can offer counties with officers that they regard it necessary in carrying out functions of the county (County of Washington, 2014). Referendum has influenced the local politics of Washington. It has helped to protect the rights of the citizens through direct democracy. Therefore, it has enabled the citizens of Washington to eliminate government that is representative and to remedy it when it turns to be misrepresentative. In addition, the petition process has been utilized in the county government of Washington. It has given the citizens of Washington superiority that is automatic and sovereignty above government that is representative. More over, the recall is constitutionally defined for the citizens of Washington. It allows citizens to remove and substitute a public official before the term ends in the office. Citizens initiate the process of petition, and if it goes through it eliminates an official elected from office through recalling the official’s elections. Besides, democratic reform trilemma has also brought great influence to the citizens of Washington based on three characteristics. These characteristics include participation, deliberation, and equality (Washington County, 2014). Participation enhances extensive participation in the process of decision making by the affected people. Deliberation enables a balanced discussion where all main points of view are prejudiced based on

Answer 3 questions about art museums Essay Example | Topics and Well Written Essays - 250 words

Answer 3 questions about art museums - Essay Example The museum shop reminds patrons that the art works they are seeing are displayed by an organization that is reliant on funding and profit. This is a significant realization as it necessitates that the museum be considered with the same analytical lens as one would apply to traditional businesses. This has implications for nearly all decision-making in the institution. Another question is whether artists should strive to make art that resists being commercial. In these regards, it seems that there is nothing inherently wrong with being commercial, or using a commercial aesthetic. Artists that specifically attempt to cultivate commercial values, however, are witnessed as suspect compared to artists that more naturally and authentically produce their art. The notion that art can be produced naturally, or rather can be produced ‘natural’ and ‘authentically,’ however, is not entirely understood as even being

Organic food Essay Example for Free

Organic food Essay We have all heard the phrase â€Å"What you don’t know won’t hurt you† and it has undoubtedly applied to many situations in our lives that we are still unaware of. We like to toss around this phrase without worrying too much about what it implies because that is the whole point of the phrase, not to worry. When it comes to what we are putting into our bodies, though, what we do not know can indeed hurt us immensely. In the United States, we have grown accustomed to not thinking much about what we are consuming. The main factors we look for in food are taste and price. We live in a consumer society where money rules our nation, it rules our lives, and it rules us. Money has become the main focus for every decision we make, but when it comes to something as important as our health, should we look at a few other factors? With societies concerns focusing on wealth and profit, there is no surprise that the food industry finds the cheapest ways to produce the most food. Consequently, this produces many negative effects on aspects of our lives such as our health and the environment. When choosing what foods to consume, we should begin to pay more attention to factors other than the price tag. The food industry obviously plays a big role in this epidemic of processed food, but they are not the only ones to blame. Yes they are the ones taking advantage of our ignorance by mass-producing cheap food that they know we will not think twice about, but the ignorance is our fault. Author of The Omnivore’s Dilemma, Michael Pollan, describes the current foundation of the food industry, â€Å"Our food system depends on consumers’ not knowing much about it beyond the price disclosed by the checkout scanner. Cheapness and ignorance are mutually reinforcing† (Pollan 245). Pollan is correct in his assumption that most Americans do not know much about their food besides how much it cost. Most of them are not even aware that they do not know what is in their food. They subconsciously assume that chicken is chicken and cheese is cheese, but unfortunately that is hardly ever the case. Many people choose to live along these guidelines of â€Å"ignorance is bliss† by not paying attention to the horror stories of the food industry; they turn their heads from documentaries on animal treatment and plug their ears at the mention of the real ingredients of their precious snacks. As long as the food they are eating tastes good and did not cost a lot of money, they are content with not knowing how unhealthy it might be. Pollan further explains another reason people buy the cheapest available food: It makes good economic sense that people with limited money to spend on food would spend it on the cheapest calories they can find, especially when the cheapest calories—fats and sugars—are precisely the ones offering the biggest neurobiological rewards. (Pollan 108) People with lower incomes are confined to buying cheap food, typically the most processed and unhealthy food, because with their limited funds they cannot afford to care about the quality of what they are eating. They buy what is cheapest because that is all they can get. As long as they have food in their stomachs, they do not complain or worry too much about the side affects. Eating food that may not be very healthy definitely outweighs the alternative of eating nothing and starving. Americans are ignorant of the food that they purchase either because they choose not to educate themselves or because they really have no choice. Either way, they are missing out on other possibilities of obtaining food that have many advantages. Not knowing what our food is made of also prevents us from knowing what alternative food options are available to us. Because we see no problems with our current food choices, we see no reason to discover new ones. The processed food at the supermarket is all we know because it is the most convenient and affordable from of nourishment we can obtain. Pollan’s book includes the testimony of someone who buys food from a local, organic farmer, â€Å"†¦for me it’s all about the taste, which is just so different—this is a chickinier chicken. Art’s chickens just taste cleaner, like the chicken I remember when I was a kid† (Pollan 252). The food available from local farmers is not only better for our health and the environment but it also tastes better. We have grown accustomed to the artificially flavored food we buy from grocery stores and do not realize that the food we eat could taste better and more natural. The locally grown food tastes healthier and more natural because that is precisely what it is. The artificially engineered taste of chicken in a common chicken nugget is not what a chicken should taste like. Besides enhanced taste, buying from local farmers offers many other benefits as well. An organic farmer interviewed in The Omnivore’s Dilemma explains some more benefits of buying locally, With our food all of the costs are figured into the price. Society is not bearing the cost of water pollution, of antibiotic resistance, of food-borne illnesses, of crop subsidies, of subsidized oil and water—of all the hidden costs to the environment and the taxpayer that make cheap food seem cheap. (Pollan 243) One of the main reasons why people do not want to look into these alternative methods of eating is because they are more expensive. People overlook these opportunities because the organic food appears overpriced, but when you evaluate all these factors it might not be as overpriced as you might think. Yes the food is more expensive but it stands true that you get what you pay for. When paying more, you are receiving a whole lot more that benefits your health, community, and environment. The extra money that would be spent on food, you might save on your medical bills and taxes. Locally produced food is healthier for you and it carries a much less chance of containing disease and illness. Another bonus of buying from local farms: there is less pollution created than in the factories and slaughterhouses of the globalized food industry. If people became aware of alternative food options and the benefits associated with them, they would be more inclined to pay better attention to what they are buying. This would not only improve ones personal health, but also the environment. Although money remains a very important role in deciding what we purchase, it would benefit us to consider a few other aspects of the food that we buy. Paying attention to details such as what goes into the food, where it is produced, and how it is produced would lead us to make healthier decisions. More often than not, a satisfying answer to these questions will not be found in the food at our local supermarkets, but rather a local farmer. Buying from these farmers would mean supporting a healthy environment and body. Their production methods are healthier and much more environmentally friendly than any factories in a big-name food industry. While it may seem that this is a simple choice, many Americans will continue to ignore these truths. When it comes down to it, money rules everything and it will take a lot more than the promise of better health for people to overlook a price tag. They say ignorance is bliss, but when that ignorance leads to decisions that contaminate our bodies and our environment, the bliss will be short lived.

Oedipus the King Essay Example for Free

Oedipus the King Essay In Sophocles Oedipus the King, the themes of fate and free will are very strong throughout the play. Only one, however, brought about Oedipus downfall and death. Both points could be argued to great effect. In ancient Greece, fate was considered to be a rudimentary part of daily life. Every aspect of life depended and was based upon fate (Nagle 100). It is common belief to assume that mankind does indeed have free will and each individual can decide the outcome of his or her life. Fate and free will both decide the fate of Oedipus the King. Both sides of the argument can be greatly supported. The Greeks believed in the idea that personality of the individual greatly affected his or her life (Nagle 120). Their personality was what decides their own free will. A wise man will make good decisions in his life; an ignorant and stubborn man wont be so fortunate. The character traits of a person have a certain positive or negative affect on the choices that he or she makes. For Oedipus, one of these attributes was the desire for knowledge and truth about his own existence. This driving force in the play led to the truth of his origin. This ties in with his own aspect of free will. His free will is based on his drive for knowledge. Throughout the entire play, Oedipus pushes Tiresias, Creon, Jocasta, the oracle, the messenger, and the shepherd for information regarding his beginnings. Each one of these characters in some way or form refused to give him a thorough answer. As he draws closer to the answer, another character tries to stop his journey. Oedipus continues moving onward even though others request he didnt. Oh no, listen to me, I beg you, dont do this. Listen to you? No more. I must know it all, see the truth at last (Sophocles 195). His desire for truth kept pushing him to continue his search, ultimately leading to his downfall. The entire time Oedipus had the capability to discontinue the plight. However he made the independent decision to continue. Another instance where choices directly linked Oedipus to the prophecy was at the crossroads. Oedipus demonstrates an important trait in his character, stubbornness. This trait is visible when Oedipus reacted to the man pushing him aside at the crossroads. the one shouldering me aside, the driver, I strike him in anger! . I killed them allevery mothers son! (Sophocles 189). In ancient times when a caravan was coming down the road they usually pushed you to the side. Oedipus didnt like this and flipped out, killing all of them. It was his stubbornness that caused this to happen. His personality led to the decision to kill the caravan and unknowingly, his father too. If he were a wise and content man, then his decision would have differed. When Oedipus defeated the Sphinx by solving the riddle, he could have refused to take the missing kings throne. He could have also declined to marry the former kings wife, unaware that the queen was his own mother. He accepted both of these without any regrets. If his decision was different it might have altered the course of events in the future. His personality made sure that the decisions went the way they did. These choices were made by Oedipus with his own free will, his own decisions. He didnt have to accept these gifts, but did none the less. These conclusions would lead to his own demise, but they were his own mistakes, not fate. Free will can also be found in the actions of Jocasta and Laius. The choices they made were not made by their own judgement, but rather reactions to a situation that neither of them was prepared to deal with. Upon hearing the prophecy that foretold the future sins in their household; they made a harsh decision out of fear. They had little Oedipus sent to die at the foothills of a mountain. This reaction seems very cruel, but back in ancient times it was very natural. Being that an oracle foretold the prophecy, Jocasta and Laius responded as any Greek parents would. They solved the problem by removing Oedipus from the equation, but in the end their decision wasnt the right one. This leaves the readers of the play to wonder what might have happened if Jocasta and Lauis never sent Oedipus to die as an infant. Would the prophecy still have taken place? It seems that it wouldnt have, because Oedipus wouldnt have engaged in the misled wandering after he left his adopted home. Oedipus would have had no reason to fulfill the prophecy, but that is another question that we dont know. On the other hand, if Oedipus didnt listen to the prophecy suggested to him in Corinth, he never would have returned to Thebes to carry out his destiny. All these instances can be looked at that free will was the deciding factor. Was it really? Fate can also be looked upon in every instance, equally a strong argument against free will. Oedipus desire for knowledge can also be looked at by the standpoint of fate. He was born with his own stubbornness. The Gods themselves made him that way and it can not be changed. No matter what his decisions were, their gift to him will lead to the path they gave him. He cant escape the fate the Gods have given him. He kept pushing farther and father, but it just led to his downfall. Nothing he could have done would have stopped that. The prophets make this clear in their prophecies throughout the text. All the premonitions they say come true. They cant be avoided because the Gods made you with your personality and it controls your life. Ultimately they control you. When Oedipus reaches the crossroads, it was fate that led to the events that took place. Short work, by god-with one blow of the staff (Sophocles 189). This quote reveals that the gods did play apart in the events that took place. Oedipus prophecy was to kill his own father. Unwillingly because of his stubbornness Oedipus struck down and did indeed kill his father. Because the gods gave him this trait, his fate was unavoidable. The traits of Oedipus would generate the right sequence of events that would eventually lead to his prophecy coming true. Oedipus personality was the cause of the events. His free will blended in with the fate given to him by the gods. All together it was fate that decided these actions. The prophecy given to Lauis and Jocasta is also another example of unavoidable fate. Even though it wasnt there own choices to get rid of their son, their reaction to the prophecy set up the events for the future. If they never sent Oedipus to die at the mountainside, he most likely never would have killed Lauis at the crossroads. Their reaction was to a message given to them by the Gods. The Gods dictated what was going to happen. They told the prophet to give out the prophecy. Leading to the vanquishing of little Oedipus. All along every action leads to ones fate in life. The greatest show of fate in the text is when Oedipus gauges his eyes out with the golden clips. He does this in reaction to the events that take place. Oedipus was aware that he alone was responsible for his actions and gauged his own eyes out. That is the free will standpoint on the issue. Oedipus was at the same time not responsible for his actions. The gods controlled his personality and therefore controlled the outcome of his life. If Oedipus realized this he might not have taken his own sight. The gods use their power to provoke humans free will. They were responsible for the demise of Oedipus, but in the same time convince the human that it was there fault. Free will and fate can be related to every aspect of Oedipus the King. The gods who control fate manipulate the thinking and concepts in humans free will. Ultimately fate is what overcomes all. It may not seem like it, but free will was given to mankind by the gods or God. So in turn the gods decide the fate of everybody when they created man. It was already decided and can not be changed. One can still argue the position that free will is more dominant, but if you relate to creation and how the gods made man, fate overcomes. In Oedipus the King, Sophocles made it clear to his fellow Greeks that mankind has the ability, even with prophecies and oracles, to make choices free from influence of divine forces. He also shows that fate does play a part in humans lives too. They tie into each other for a direct balance. Overall, fate is the divine power that controls free will and determines ones life.

Histamine Stimulated Small Intestine

Histamine Stimulated Small Intestine The longitudinal smooth muscle of the guinea-pig ileum small intestine contracts in response to acetylcholine. These contractions can be reduced by the application of adenosine and related compounds. The guinea-pig ileum is innervated by the enteric, sympathetic and parasympathetic divisions of the autonomic nervous system. The parasympathetic and enteric fibres release acetylcholine which acts on muscarinic receptors. The action of adenosine and its receptor antagonists can be assessed by comparing electrically induced contractions via electrical field stimulation and histamine induced contractions. Electrical field stimulation contractions cause presynaptic release of acetylcholine to produce contractions where as the histamine induced contractions cause postsynaptic contractile responses. Throughout this study adenosine and its receptor antagonist actions will be investigated and compared using electrical field stimulation and histamine. The contraction of the gut In gastrointestinal smooth muscles, researches show that there are two types of muscarinic receptors types that are present as targets to the neurotransmitter acetylcholine (Okamoto et al., 2002).Acetylcholine and its derivatives produce contractions by activating muscarinic receptors. The muscarinic receptors types are known as M2 and M3. Binding Studies have portrayed that the number of M2 receptors is greater than that of the M3 receptors however functional studies have shown that M3 muscarinic receptors play a fundamental role in mediating the contractile response (Eglen et al., 1996) and the functional role of M2 exists as unclear (Clague et al., 1985). The M3 receptor is coupled with G proteins, causing activation of phospholipase C and formation of inositol trisphosphate and diacylglycerol, which are expected to contribute in muscarinic receptor mediated smooth muscle contractions (Unno et al., 2005). They also mediate relaxation due to the release of nitric oxide from neighbo uring endothelial cells. M3 receptors in visceral smooth muscle contribute to the smooth muscle stimulating effect of muscarinic agonists. However the muscarinic receptor most abundant in the ileum is the M2 which cause an indirect contraction of the guinea-pig ileum by preventing the relaxing effect of drugs (Ehlert and Thomas, 1995). Both muscarinic receptor subtypes are activated by acetylcholine and produce a contractile response; however they vary in their transduction mechanisms and signalling pathways. Adenosine Adenosine has numerous diverse roles in normal physiology; such roles include promoting/maintaining sleep, regulating state of encouragement as well as local neuronal excitability and coupling cerebral blood flow to energy demand (Dunwiddie and Masino, 2001). It exists free in the cytosol of all cells and is transported in and out of all cells mainly using a membrane transporter(Rang et al., 2007). Under normal conditions, adenosine is formed intracellularly as well as extracellularly (Fredholm et al., 2001). ATP is stored in vesicles and released by exocytosis. It is also available in the cytosol of cells and is taken up and released via a specific membrane transporter. Released ATP and ADP are rapidly converted to adenosine by the action of tissue nucleotides. Studies have shown that there are pathways that contribute to adenosine formation, a) by the action of adenylate kinase and cystolic 5-nucleotidase, b) formation from hydrolysis of adenosine 3, 5 phosphate and c) formation by the action of S-adenosylhomocysteine (SAH) hydrolase. The pharmacological effects of adenosine include smooth muscle relaxation and inhibition of nerve activity, lipolysis and platelet aggregation(Daly et al., 1983). There is evidence that stimulation or inhibition is of adenylate cyclise is involved in adenosine action and therefore it has been concluded that adenosine is mediated by cyclic AMP. Based on its ability to inhibit cell function and thus minimise the metabolic requirements of cells, one of its functions may be as a protective agent released when tissue integrity is threatened. Adenosine exerts its physiological actions activation of a number of specific cell surface receptors. There are four different adenosine receptors known as A1, A2A, A2B, and A3. Some characteristics of these receptors are presented in Figure 1a. These subtypes have been distinguished on the basis of their agonist and antagonist selectivity. They belong to the G protein-coupled receptors. Mechanism of Adenosine action Adenosine A1 receptors are negatively coupled to the inhibition of adenylate cyclase, however they can act through other pathways such as stimulation of phospholipase C, activation of potassium channels and inhibition of N-type calcium channels (Zizzo et al., 2009). A1 receptors are coupled to Gi and G0 proteins and lead to inhibition of adenylate cyclase and consequently cause a decrease in cAMP (Ranjit, 2008). Adenosine A2A and A2B are coupled for activation of adenylate cyclise whereas A3 receptors have been shown to stimulate phospholipase C and D, to inhibit adenylate cyclase and to activate ATP sensitive potassium channel (Ralevic and Burnstock, 1998). Activation of these receptors require comparatively high amounts of adenosine. A2A and A2B receptors have a high and a low affinity for adenosine respectively. Receptor Subtype A1 A2A A2B A3 Transduction mechanism Inhibits adenylyl cyclase Activates adenylyl cyclase Activates adenylyl cyclase Inhibits adenylyl cyclase Primary distribution Brain (cortex, cerebellum, hippocampus). Dorsal horn of spinal cord. Eye, adrenal gland, atria Spleen, thymus, leukocytes, blood platelets. Straitopallidal GABAergic neurons, olfactory bulb Caecum, colon, bladder Testis, mast cells Tissue functions Antinociception, Hypothermia. Sedation, Sleep, Inhibition of lipolysis, Cardio and neuroprotection Reflex tachycardia, vasodilation, inhibition of platelet aggregation, sleep protection against ischemia Relaxation of vascular and intestinal smooth muscle, cytokine production, inhibition of cell proliferation Mast cell degranulation, coronary vasodilation and protection from reperfusion Selective antagonists DPCPX PSB 36 SCH 58261 PSB 1115 potassium salt MRS 3777 hemioxalate Figure 1a: Summary of adenosine receptors. Adenosine and the enteric functions of the Gut The enteric nervous system (ENS) consists of a compilation of neurons in the gastrointestinal nervous system which is capable of functioning independently of the central nervous system. It moderates motility, secretion, microcirculation, inflammatory and immune responses of the gastrointestinal tract (Altaf and Sood, 2008). The ENS is composed of extrinsic, which consists of parasympathetic and sympathetic divisions and the intrinsic component which encloses neurons. Intestinal functions results from an interaction between the ENS, smooth muscle and the mucosal/immune system. The network is regulated by several mediators; however there is consolidating evidence that adenosine is a significant regulating agent (Bueno, 2000) (Wood, 2004). Studies show that in the small intestine adenosine and adenosine derivatives where found to inhibit cholinergic transmission in guinea-pigs via a prejunctional action on neurotransmitter release (Gustafsson et al., 1978). The action of the A1 receptor s allowed mediation of the inhibitory action of adenosine in the cholinergic transmission(Shinozuka et al., 1985) of motor neurones innervating circular and longitudinal smooth muscle however A2A receptors have been reported to reduce the cholinergic motor responses(Gustafsson et al., 1985a; Gustafsson et al., 1985b). Histamine Histamine has a role as a primary transmitter or neuromodulator and it is widely distributed within mammalian tissues. (Izzo et al., 1998). Histamine is a vasoactive substance to be identified in the body which can rapidly metabolise and holds properties of being highly polar and not diffusing readily across cell membranes or the blood-brain barrier. It is stored in mast cells and basophils of blood and has two receptors known as H1 and H2. The release of histamine could cause changes in the cardiovascular system and induce anaphylactic shock. Histamine has been shown to induce gastric acid secretion through the H2 receptors linked to cyclic AMP production in oxyntic cells. Researches show that gastric cells of the guinea-pig may have a class of binding sites for histamine which shows no relationship to adenylate cyclase and the H2 receptor. Histamine creates a spasmogenic effect on the intestine that results from H1 receptor stimulation(Guy A. and Settipane, 1988-1989). There are three histamine subtypes known as H1, H2 AND H3 and all three have been identified to be present in the guinea pig small intestine. Studies show that H1 receptor subtypes mediate the contraction of the longitudinal muscle in the small intestine (Izzo et al., 1998). However researchers also state that the effect of histamine is predominantly due to the interaction with H1 receptors located on smooth muscle cells and moderately due to the interaction H2 receptors present on myenteric plexus interneurones (Bauer and Matusak, 1988). AIMS The aim is to confirm the prejunctional action of adenosine and examine whether adenosine has the additional ability to relax the smooth muscle directly. The project will use histamine to contract the smooth muscle and the objective is to find out whether adenosine can reduce these contractions and if so is the concentration range similar to that needed to inhibit the contractions to the electrical field-stimulation? It will also be investigated what adenosine receptor subtype is involved (A1, A2A, A2B, A3 identified using selective antagonists). METHOD Animals and preparation of tissue Dunkin Hartley guinea-pigs (250g +) of male sex that had previously been fed Harlan 2040, the guinea-pig diet and ad lib filtered tap water, were obtained from Harlan UK. They were group housed and provided with grade 6 woodchip and hay bedding. Their enrichment consisted of plastic and cardboard fun tunnels, plastic igloos and gnawing blocks. Furthermore they were kept at room temperatures of 19-23 °C and at room humidity of 45-65%. They were provided with 12 hours light and 12 hours of dark lighting. The guinea-pigs were stunned by a blow to the head and sacrificed by exsanguination. Two segments of 3cm length were removed from the distal part of the small intestine, for each tissue the ends were tied with cotton threads to the tissue holder and then suspended in 20ml organ baths containing Krebs solution (composition in mM: NaCl, 118; NaHCO3, 25; Glucose, 11; KCl, 4.7; CACl2, 2.5; KH2PO4, 1.18; MgSO4, 1.18). This was aerated with 95% O2 and 5% CO2 and maintained at 37 °C. The tissues were left for 30minutes to equilibrate under a resting tension of 1g before starting the stimulation. Experimental protocol The organ baths were equipped with parallel electrodes which allowed electrical field stimulation to be transmitted at a frequency of 0.1Hz, 40V, 0.5ms pulse duration. Contractions of the ileum were measured with isometric transducers (ADInstruments Force Transducers), amplified and recorded onto a data capture system (Lab Charts on the PC). The tissues were allowed to stabilise in the organ baths in order to reach steady contractions. Figure 1b represents the experimental set up. C:UsersHomeDocumentsDSC00308.JPG Figure 1b shows the laboratory designed set up for the experiment, with a set of two organ baths. There were several parts (a-e) to the experiments to be carried out on the ileum. n is the number of ileum used throughout the experiment n=18. The number of experiments carried out on the ileum was 56. Effect of Adenosine-the experiment consisted of stimulating the tissues continuously with electrical field stimulation and adding cumulative concentrations of adenosine (10-11M 10-4M) to the organ baths and the responses were recorded. Effect of Histamine- the tissues were stimulated with histamine, cumulative concentrations of histamine (10-11M 10-4M) were added to the organ bath and responses were measured. The concentration 110-6M gave the maximum response and a steady contraction, it was used to contract the tissue with adenosine. Effect of Adenosine in the presence of Histamine- the concentration of histamine that gave the maximum and steady response was added to organ bath. The tissue was permitted to stabilise in order to reach steady contractions. Once reached, cumulative concentrations of adenosine were added (10-8M 10-4M) in order to observe the responses of the ileum to adenosine in the presence of histamine. Effect of PSB36(10-8M) SCH58261(10-7M) to confirm identity of receptors being investigated, cumulative dose-response curves for induced contractions by histamine were observed for adenosine in the presence of selective antagonists, PSB36 and SCH58261. An experiment was also carried out, which involved electrical field stimulation to contract the tissue, adenosine was added in the presence of these antagonists. Effect of Atropine Atropine concentrations of 10-6M 10-7M were added to establish the effects of atropine on the electrically field stimulated ileum. For each drug that was being tested except atropine, the experiment was repeated at least six times. The tissue was washed out three times at least after an experiment was completed and was allowed to recover before another experiment was carried out. The electrical field stimulation was also switched off each time the tissue was washed out. Chemicals and drugs The drugs that were used consisted of Adenosine hemisulphate salt, Histamine diphosphate salt and Atropine sulphate salt which were all purchased from Sigma-Aldrich, Poole, UK. PSB36 and SCH58261 and DMSO (Dimethyl sulfoxide) were purchased from Tocris -Cookson, Bristol, UK. All drugs were dissolved in distilled water with exceptions of PSB36 AND SCH58261 which were diluted with DMSO.10ml of stock solution were made up in each case. Statistical Analysis All drug concentrations presented were final bath concentrations. The drug effects were expressed as twitch contraction (g). All data were given as means  ± S.E.M, where n represents the number of animals from which tissues were taken and on which observations were made. Inhibitory effects by adenosine in the field stimulated guinea pig ileum were measured and the responses of ileum twitch contraction were recorded for each concentration applied. This was repeated when using adenosine receptor antagonists. Adenosine responses were fitted onto concentration-response curve. Effects of histamine stimulated guinea pig ileum were also recorded. Adenosine responses and its receptor antagonist response were measured and plotted. 3.0 RESULTS a. b. Figure 2. The effect of adenosine concentrations in the guinea-pig ileum. Data are means  ±S.E.M and are expressed as an average of contractions (g). a. Representative traces showing inhibitory responses induced by adenosine. b. Concentration response curve for adenosine representing the average twitch response (g) when cumulative adenosine concentrations were added. Each point with bar represents the mean  ± S.E.M (n=6). Figure 3a: Original trace illustrating twitch response abolished by atropine 10-6M final bath concentration. b. c. Figure 3. Influences of atropine and potent and selective A1 adenosine receptor antagonist PSB36 10-7M AND 10-8M on guinea-pig ileum. b. Twitch responses of the guinea-pig ileum preparation to electrical field stimulation in the presence of PSB36 10-7M (n=6) and PSB36 10-8M (n=4), compared to twitch responses to adenosine alone. The experiments carried out were not paired. Each point with bar represents the mean  ± S.E.M. c. Contractions of the guinea-pig ileum preparation stimulated by histamine in the presence of PSB36 10-7M (n=6) and PSB36 10-8M (n=4), compared to responses to adenosine when stimulated with histamine (n=6). The experiments carried out were not paired. Each point with bar represents the mean  ± S.E.M. a. b. Figure 4. Summarises the effect of potent and selective A2A adenosine receptor antagonist SCH58261 10-7M on guinea-pig ileum. a. Twitch responses of the guinea-pig ileum preparation to electrical field stimulation in the presence of SCH58261 10-7M (n=6), compared to twitch responses to adenosine alone. The experiments carried out were not paired. Each point with bar represents the mean  ± S.E.M. b. Contractions of the guinea-pig ileum preparation stimulated by histamine in the presence of SCH58261 10-7M (n=6), compared to responses to adenosine when stimulated with histamine (n=6). The experiments carried out were not paired. Each point with bar represents the mean  ± S.E.M. Figure5a. A concentration-response curve illustrating the effects of adenosine on the guinea-pig ileum when the tissue is stimulated with histamine. . Each point with bar represents the mean  ± S.E.M (n=6). Figure 5b. Responses of the guinea-pig ileum to cumulative concentrations of histamine. Each point with bar represents the mean  ± S.E.M (n=8). Electrical field stimulated guinea-pig ileum produced reproducible twitch responses to adenosine. Adenosine concentrations ranging from 10-8M final bath concentration caused concentration dependent inhibitory effects. Administration of increasing adenosine concentrations decreased electrically evoked acetylcholine release from the cholinergic nerve endings of the ileum (Figure2). Figure 2b clearly portrays that adenosine has no effect at low final bath concentrations of 10-11M. Atropine 10-6M final bath concentration abolished the twitch responses to electrical field stimulation confirming they were produced by cholinergic nerve stimulation (Figure3). In the presence of selective A1 adenosine receptor antagonist PSB36 10-7M and 10-8M concentration and electrical field stimulation, the twitch responses to adenosine decreased, when adenosine was applied at higher concentrations, the twitch responses became smaller as acetylcholine release was inhibited and completely prevented by PSB36. Figure 3a shows the curve shifted to the right when PSB36 10-8 was administered compared to the curve of adenosine. When PSB36 10-7 was applied there is a slight shift of the curve to the right compared to the adenosine curve. The effects of the antagonist PSB36 are seen significantly at 10-8M final bath concentration as the shift of the curve is greater. The highest response the ileum produced was as at adenosine concentration of 1 x 10-8M, the responses lowered slightly at 1 x 10-6M and consequently decreased rapidly at 1 x 10-5M final bath concentrations. Histamine induces contractions in the ileum. Addition of cumulative concentrations of adenosine in the presence of PSB36 10-7M produced small responses compared to the contractions produced in the presence of PSB36 10-8M. The effect of PSB36 10-8M caused a rightward shift compared to the curve representing the effect of adenosine in the presence of histamine (Figure 3b). Electrically field stimulated ileum in the presence of the selective adenosine receptor competitive antagonist SCH58261 produced smaller responses (Figure 4a). Following administration of cumulative concentrations the responses decreased however produced no right shift in the dose response curve. Histamine excites the tissue causing it to contract and producing a high response, when adenosine is applied in the presence of SCH58261, the responses are inhibited and acetylcholine release is decreased and thus there is a decrease in the shape of the curve in Figure 4b. The results expressed in Figure 5a illustrate the inhibitory effects of adenosine in the ileum. Figure 5b illustrates the effects of histamine concentrations on the ileum. The experiment was carried out to investigate the best concentration to use so that a maximum and strong, reproducible contraction would be produced; the figure confirmed 110-6M final bath concentration to give the highest and steady contraction of the tissue. Moreover this permitted to obtain a dose-response curve for adenosine with histamine providing a suitable starting concentration for each drug at 110-8M. DISCUSSION The results of this present study show that adenosine plays an inhibitory role on muscular contractility in guinea-pig ileum. Adenosine prevents the neuroeffector transmission in guinea-pig ileum. The action of adenosine appeared to be cholinergic prejunctional in nature, this is portrayed when adenosine is applied to electrically field stimulated guinea-pig ileum(Gustafsson et al., 1985b). The action of adenosine on histamine stimulated guinea-pig ileum in the absence and presence of adenosine antagonists also indicates reduction in neuroeffector transmission however due to postjunctional action. The effect of adenosine on the guinea-pig ileum can be observed in Figure 2. Adenosine produced a dose-dependent depression on the response. It reduced the electrically evoked acetylcholine release from the ileum. A1 and A2 receptors have been reported to reduce acetylcholine release in the gastrointestinal tract(Tomaru et al., 1995). Adenosine released from neuronal endings is thought to have direct actions on smooth muscle as they illustrate relaxant neurotransmitters in the gastrointestinal tract(Storr et al., 2002). Atropine is a competitive antagonist for the muscarinic acetylcholine receptor, consequently when applied to the ileum at 10-6M final bath concentration; there is rapid inhibition of response confirming that the twitch responses were produced by cholinergic nerve stimulation. Adenosine inhibited the twitch response of the electrically stimulated guinea-pig ileum preparation, in the presence of PSB36 10-8M final bath concentration there was a right shift in the adenosine curve thus interpreting that higher concentrations were required to lower the twitch response. The general trends that Figure 3a displays is that the curves have the same form; the linear proportions of the curves are parallel. The traces help to show the changes in the response curve to adenosine and adenosine selective receptor antagonist PSB36. There is a slight fall in tension when adenosine 310-7M was applied in the presence of PSB36 10-8M; however there was a rapid decrease when adenosine 110-5M was administered causing the right shift in the Figure. Upon cumulative additions of adenosine to field stimulated guinea pig ileum the concentration required to inhibit acetylcholine release was of 310-7M, the effects diminish once concentration of adenosine 110-5M was added providing evidence that adenosine has the ability to relax smooth muscle in the ileum. Since PSB36 is a potent and selective A1 adenosine receptor antagonist, the A2A receptors increase electrically induced twitch contractions in the guinea pig ileum, which contributes to assistance of acetylcholine release (Storr et al., 2002). The effects of adenosine in the presence of PSB36 10-7M 10-8M to histamine stimulated guinea pig ileum can be observed in Figure 3b. Histamine administration to the guinea pig ileum caused a tonic histamine contraction which was followed by after-relaxation response, and application of adenosine inhibited the acetylcholine release. The ileum responses were reduced significantly with lower concentrations of adenosine in the presence of PSB36 10-7M and 10-8M compared to the concentrations of adenosine required in the electrically field stimulated ileum confirming that A1 receptors are the subtype present in the guinea pig ileum which cause the inhibition of acetylcholine release. SCH58261 did not significantly affect the position of the rightward shift however additions of cumulative adenosine concentrations caused reduction in the tension produced by the ileum. Large standard error bars can be observed in the figures, these may be due to human handling errors, i.e. micropipetting errors, administrating less or more concentration of adenosine or antagonists. Protein build up causing contamination in organ baths can also contribute to acquiring inaccurate results. Particular cells of the tissue may have become inactive at that moment of time. Furthermore it could be that the piece of thread holding the tissue may have become loose i.e. equipment errors and consequently tension was not measured accurately. It could also be due to unknown errors. Evidence that adenosine inhibits cholinergic neuroeffector transmission in the ileum by a prejunctional action on acetylcholine release can be of functional importance as adenine compounds are released during stimulation of intestinal nerves (Tomaru et al., 1995). Antagonists selective for adenosine receptors are beneficial in the research treatment of numerous conditions including cardiovascular, neurodegenerative and inflammatory diseases. In summary, the present study has confirmed the existence of presynaptic A1 receptors on the parasympathetic nerve terminals in the guinea pig ileum which upon activation causes inhibition of electrically induced neurogenic, cholinergic twitch contractions.

Mycosis Fungoides Essay -- Biology, T Cells

Mycosis fungoides is a main subtype of a cutaneous T cell lymphoma (CTCL), in which a heterogeneous collection of lymphomas develop into malignant cancer cells, primarily affecting the skin. This disease can be distinguished from other cutaneous T cell lymphomas by its unique clinical and histologic features (Armitage et al., 2010). Mycosis fungoides can be treated several different ways and is dependent on several factors such as the stage of the cancer, health of the patient, presenting symptoms and patient-specific issues (Parker & Bradley, 2006). Traditional therapies for mycosis fungoides involved radiation therapy, oral psoralen with UVA light therapy and narrow- and broadband UVB light therapy. Recently, novel therapies have been established to treat CTCL and several of them are starting to become routine therapies for the erythrodermic subgroup of mycosis fungoides. This paper will discuss the historical background of the disease as well as the new techniques that have been u sed within the past few years and the traditional methods of treatment. T cells are genetically prepared to protect and survey the human body from any environmental stressors, foreign agents and malignancy. Some of these T cells are programmed to protect the skin. Once the body is infected with T lymphocytes, the T cells infiltrate the skin, work together to eradicate the allergen and eventually they undergo the process of natural cell death. However, when specific skin-homing T lymphocytes infect the skin, they then clonally expand and are sometimes unable to exit the skin compartment. Once the lymphocytes accumulate within the skin, the reaction is then known as a rash. This proliferation of abnormal cloning of T cells within the skin distinguishes ... ...ter researching mycosis fungoides, I have learned that the cause of this disease is unknown and unless detected at an early stage, it is most likely not curable. What are fortunate for patients with mycosis fungoides are the numerous therapeutic options which I find to be remarkable. Since the treatment options are mainly palliative, I have realized the goals of therapy for this disease are symptom relief and consideration for their quality of life. Although most techniques are chosen based upon clinical stage of the disease, what I find most promising is total skin electron beam radiation therapy. With this type of technology being around for several years, and continuously updating to modern techniques, I find it most beneficial to patients. However, there are several options available for patients and being able to combine different therapies is in their favor.

Essay on the Influence of Mary Shelley’s Life on Frankenstein

Influence of Mary Shelley’s Life on Frankenstein      Ã‚  Ã‚  Since its publication in 1818, Mary Shelley's Frankenstein has grown to become a name associated with horror and science fiction. To fully understand the importance and origin of this novel, we must look at both the tragedies of Mary Shelley's background and her own origins. Only then can we begin to examine what the icon "Frankenstein" has become in today's society.      Ã‚  Ã‚  Ã‚   Mary Godwin was born in London in 1797 to prominent philosopher William Godwin and well-known feminist and author Mary Wollstonecraft Godwin. Shortly after Mary's birth, her mother died of complications from childbirth, and this event set the stage for the strained relationship between Mary and her father. Godwin blamed Mary for her mother's death and put her in the care of her unqualified stepmother, who favored her own children and forced Mary to do tedious housework. Godwin felt that punishing Mary would satisfy his grief, and consequently Mary became withdrawn in her studies. Her talent for writing is believed to have saved her from premature suicide.      Ã‚  Ã‚  Ã‚   Possibly as an attempt to be accepted by her father, Mary immersed herself in literary studies and her father's intellectual conversations with other philosophers. She attempted to compete with her mother's legacy by continuously writing. It was reported that Mary's "attempts to compete with her dead mother reached obsessive proportions by the time she turned seventeen." "When Mary was seventeen," writes Samuel Rosenburg, "she began taking her books and writing material to the nearby Old St. Pancras Church, where her parents had been married and where her mother was buried. There, seated in the graveyard behind the church, th... ...ience fiction. From this novel, many other versions have spawned, each one versions of the legendary novel by 19-year-old Mary Shelley.    Works Cited Florescu, Radu. In Search of Frankenstein. Boston: New York Graphic Society, 1975. Glut, Donald F. The Frankenstein Language: A Tribute to Mary Shelley and Boris Karloff. Metuchen: The Scarecrow Press, Inc., 1973. Shelley, Mary. Frankenstein. London: Puffin Books, 1818. Rosenburg, Samuel. "Happy 150th Dear Frankenstein," Life. March 15, 1968. taken from "the Life of Mary Shelley" document online: http://www.desert-fairy.com/life.shtml   Ã‚  Ã‚  Ã‚  Ã‚   Works Consulted http://www.mountwashingtonvalley.com/frankenstein/ http://www.cityu.edu.hk/ls/research/frankenstein/ http://www.frankensteinwaxmuseum.com http://www.rrfrankenstein.com http://www.godsandmonsters.net   

Valley Winery Case Essay examples -- essays research papers

The Valley Winery-Case 1.1   Ã‚  Ã‚  Ã‚  Ã‚  Is the management of Valley Winery doing an acceptable job of hiring and training qualified employees?   Ã‚  Ã‚  Ã‚  Ã‚  Management is the foundation of a company. They are the ones that make decisions which could make or break a company. They personify how the company and employees should act. If one is driven towards perfection in sales, many other important areas of the business could be overlooked. For example, maintenance of long term relationships with buyers would be overlooked. If management is pushing the sales reps to just go after the sale at any cost, reps could be looked at as unethical and even too pushy. Valley Winery management encourages reps to lie about how many cases of wine are sold to buyers. This is unethical and puffery. Pushing these sales reps to call their ethics into question, what does that say about management?   Ã‚  Ã‚  Ã‚  Ã‚  Pat Waller, employee of Valley Winery, was recently promoted to sales manager of the San Francisco region’s chain division. When he arrived, he was shocked to find that such a successful division had such a horrible turnover rate. How was the San Francisco division of Valley Winery obtaining their sales goals? He began to investigate and found many problems that were mainly stemming from management. The hiring process of Valley Winery needs to be revised. Mike Wehner, personnel manager for the San Francisco division, believes that employment agencies provide the most qualified applicants. If this is true, would the turnover rate be near 100 percent? According†¦., employees acquired from employment agencies yield high turnover rates. Top management places too much of an emphasis on youth and physical attributes. Sales representatives of Valley Winery should be groomed and well kept. However, youthfulness and physical attributes should not outweigh quali fications for the job at hand. Looks are important but qualifications and experience would not be overlooked. Businesses have an image they would like their representatives to project.   Ã‚  Ã‚  Ã‚  Ã‚  Once qualified sales representatives have been hired, proper training should be enforced. The Valley Winery new recruits are not given a true portrayal of everything their new sales job entails. During the hiring process, a sales hopeful is sent into the field for ... ...p;  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   -Professional Growth All of these factors can lead to or be affected by negative affectivity. This figure describes how negative affectivity can affect a person’s productivity. Negative affectivity is the state of mind a person gets in if experiencing a tumultuous work environment. Individuals that experience high negative affectivity have a negative outlook towards their job and themselves. Motivation among employees of Valley Winery is non existent. One of the top producing sales representatives, Bill Murphy, was receiving phone calls as late as ten thirty at night. These calls were routine and the objectives could be accomplished by email. Phone calls this late hurts morale and disposition of the sales force. The proposed mentoring program being developed by management and human resources will help remedy this problem.   Ã‚  Ã‚  Ã‚  Ã‚  Putting the new hiring criteria in effect at Valley Winery should create a reduction in employee loss. By retaining new employees and hiring the correct representative, training costs should be significantly downsized.   Ã‚  Ã‚  Ã‚  Ã‚  

Impact of Edsa Revolution

EDSA Revolution I In the year 1986, the Philippines was given the world’s limelight because of the nonviolent revolution to overthrow the dictatorship of Former President Ferdinand Marcos. Many countries were astounded by our country’s move and it draw much more attention because nobody died. With 2 million participants involved in the protest, the military was given a choice whether or not firing back to the protesters who are free of firearms and are only holding rosaries. And because of this the Filipino citizens were successful in overthrowing the dictatorship’s administration and the departure of the Marcos Family.The Filipino Citizens were able to taste democracy again because of the leadership of Former President Corazon Aquino after the Marcos Family left. (Santiago, 2009). As Santiago stated in her website, she detailed all the events on EDSA revolution I per day and explained it thoroughly. Reading materials like this or anything related the EDSA revolu tion makes a Filipino’s heart feel proud about what the world saw. I was not yet born during the EDSA revolution but the rest of my siblings and parents were there and experienced all the happenings.I was able to get my mother’s side of the story on what happened during the EDSA Revolution. I started to ask where she was during the EDSA Revolution (Febrauary 22-25) and said that she was at her office together with my siblings (The office where my mother is working is also our house). They were listening to updates of the events like the protests, and chaos through TV and radio. My mother was working at a printing office and she said that their clients increased because the clients were giving job orders on flyers about overthrowing Marcos’ administration.And my mother stated that the flyers they printed were distributed to people who are passing by. My mother also stated that their sales increased during that time because the job orders they received kept on com ing and coming. She said that Cardinal Sin encouraged people to join the protest on Epifanio De los Santos Avenue (EDSA) and said that when there are a lot of people, the military will have a choice whether or not to fire their bullets or let the protesters be. Even though my mother was not able to go to the protest in EDSA, she said they gave food to the people who are keeping an eye out on the rallies.My mother couldn’t join the rally because she was taking care of my siblings. But she was updated with the latest news about the progression of the rallies. After overthrowing Marcos, people rejoiced and went straight to Malcanang. Some people actually tore the pictures of the Marcos, they saw the machines used by Former President Ferdinand Marcos for his illness and it confirmed that he was really suffering from an illness. A few days after the success of overthrowing Marcos, The Marcos Family went Hawaii.Then, Former President Corazon Aquino proceeded to being the first fema le president of our country and she gained fame because of being the first female democratic president to be elected in Asia and she was able to bring back the democracy of our country. The revolution gave new insights to the Filipino citizens, my mother said that they able to know the power of people who come together and fight for what they think is wrong to the mass. And how their power as citizens value because they are also the ones in charge of choosing who will sit as president; so, they should be careful of their decision.And the Martial Law disciplined the Filipinos. Even though a lot of people are not in favor of it. It actually promoted discipline and order. My mother said that there were not a lot of changes except for the term of the president. The president had only 1 term which lasts for six years. And the dictatorship days were gone. But with regards to our country’s economic status and lifestyle, it got worst. From my mother’s story and from what I hav e read, I learned that Filipinos are people who like joining rallies involving overthrowing administrations that does not satisfy them. And they stick to what the believe in. owadays, rallying excessively does not do benefit protesters. I wonder why people were able to achieve what they are fighting for in rallies during that time. And I learned that a lot of people were really aware of all the updates about the EDSA Revolution. Social awareness was evident during that time. I discovered that when you become a voter, your responsibility if quite heavy. One vote can make or break a candidate and if a voter us not satisfied they have the freedom to say that the administration is not working well since we are in a democratic country. And also the Filipino citizens.So, before voting, think about what this candidate can do to our country or community no matter how small his place is. What matters is what the voters think and what the candidate will do satisfy his followers. And my mom sa id that Marcos had great plans for the country and I wish that there would be a president who would be able to give the country efficient projects that are feasible, so that, it can help the Filipino people rise. Reference: Santiago, Angela. (2009). â€Å"EDSA Introduction† Retrieved on January 29, 2011 from http://www. stuartxchange. org/EdsaIntro. html By: Ana Rosales

Financial Crisis

The latest world(prenominal) fiscal crisis was exploded in 2008. This was the most life-threatening fiscal crisis since the stinting depression which occurred in sass and it severely impacted the spheric pecuniary securities industry. Lots of corpoproportionns collapsed during the 2008 monetary era bulge which was puddled by breakage of groovy chain. Although ab turn out companies did not bankrupt during t assume period, they as well as had suffered great divergence. The 2008 spheric pecuniary crisis began from America. Ameri green goddess pecuniary crisis came from the prosperity of real estate.Before the 2008 planetary monetary crisis, a grown drinking chocolate of pecuniary derivatives were generated and monetary bubble became to a greater extent(prenominal)(prenominal) and more effective. Finally, Ameri laughingstock sub- overage crisis occurred which leaded to a large number of bank failure. This paper willing analyze the reason of Ameri muckle su b- run aground crisis and indicate the relevancy among shallows article, federal chest of drawers system and the 2008 global pecuniary crisis. This sample will argue that execution surmisal contributes to the 2008 global monetary corner. 2 check into of the literature 2. confidence opening Agency possibility has exposit a family between principals and agents. It in any case an solve this family relationship through a contract that sensation or more persons (the principal(s)) engage approximately former(a) person (the agent) to perform well-nigh helper on their behalf which involves delegating almost purpose making authority to the agent denser and Neckline, 1976308, citied in Lehman and Continue, 2013). 2. 2 Bad possibility and humans morality and ethical code After the collapse of Enron, Shoal (2005) potently argues that job tutor does not need to do oodles of things.In contrast, they except need to terminate some old courses which they be inst illing for their students. The reason is that the ascendent of the fares in coun mete outing practices shadower be found in the theories of management. Additionally, management practices which argon condemned argon enhanced by these theories and ideas (Shoal, 2005 75). Moreover, argumentation school brooknot address the issues of moral and ethic. Clansman, policy change and Heckler (1998 77, citied in Shoal, 2005) claim that management studies is regarded as a branch of the amicable acquirements.Namely, the issues of worry studies do-nothing be study and resolved in rule of cordial acquirements. However, Ghosted (2005 77) sozzledly argues that people use scientific focal point o explore regulation so that they draw ignored the moral and morality of humans. Because at that place atomic number 18 some cardinal basic diversities between physical sciences and business studies, some theories of physical sciences be not suitable for business studies. Furthermore, t he parts of business studies which argon related to physical (2005), steady though scientific methods (p. 7) exerts some validatory influences, the cost is expensive. Therefore, this approach denies the subjective green light of human. In addition, humans morality and ethic which are neglected by individuals are inevitable in human intentionality. Jensen and Michelin (1976, cited in Shoal, 2005 75) assert that an idea which mangers push asidenot be trusted was taught to their students in business school. As a result, when these students graduate, they plainly trust their leaders and do not realize that they should strictly maintain in the flesh(predicate) integrity.Additionally, level though Friedman (1953, citied in Shoal, 2005) ac liveledges that the profession of agents is to maximize the clear of shareholders, Shoal discounts this determine and argues that compared with finding a spick-and-span theorize by employees, it is easier that shareholder hobo sell their p otty (Shoal, 2005). Furthermore, shareholder take to be minimisation is the fundamental of the situation theory. However, Shoal (2005 81) strongly asserts that they are not relevant and points out that these research and analyses are built on incorrect assumption, which meaner they are kafkaesque.Moreover, Chicago Agenda ingrained emphasis laws and rules and against human intentionality and indicates that ethic and ethics which are only relevant with persons tooshie be removed from social science (Shoal, 2005). Nevertheless, Shoal disagrees this view and approves of the stewardship theory, because it can efficaciously give understandation to he profit of customers, employees, shareholders and their communities (Davis, Chairman and Donaldson, 1997, citied in Shoal, 2005 81). 2. 3 scope of monetary crisis The 2008 global financial recession has been described a once in a century impute tsunami (Earl, 2009 785).This is a disastrous blow to global financial community. Ballard (et al, 2009, citied in Huh et at, 2012) points out that many economists regarded the global financial crisis as the most flagitious global finance disaster since sass. Compared with only 11 banks was bankruptcy during 2003 to 2007, at least 160 American banks went broke in 2008 and 2009 (Fide, 2011, citied in Huh et al, 2012). From this statistics, it is not difficult to know how strong influence brought by this financial crisis. There is a close combine between the 2008 global financial crisis and sub- set of life crisis.Bernard (2007, citied in Hellenize and Chaos, 2012) asserts that sub- efflorescence mortgages are loans made to borrowers who are perceived to commence a high credit risk, often because they lack a strong credit history or keep other characteristics that are associated with high probabilities of indifference. Furthermore, during 1990 to 2000, cause of the IT bubble economy, the American government took some steps to pr even sot sparing downturn, much(pren ominal) as reducing delight rate, acidulous tax, decreasing the cost of sub-prime etc.Even though there were high(prenominal) risks that some of sub- prime borrowers cannot devolve bullion punctually, the sub-prime mortgage had drive an super phenomenon in that period, because this kind of debits can institute more return due to the higher hobby rate. In addition, secondary grocery store had Thus mortgagor can easier gain mortgage credit, no matter he or she is the sub- prime borrowers or prime borrowers. As a result, sub-prime mortgage market had developed rapidly.Furthermore, a large section of American best-loved to buy a field in installment mean before the 2008 global financial crisis and some of them were sub-prime borrowers. Basic and Chine (1996, citied in alteration and Chine, 2013 14) claim that people need more than enough fortune to certify their social status. This is wherefore lots of American purchased a house in installment plan. Because of the highe r interest rate, local banks were pleasured to borrow currency to these sub- prime borrowers. Goodhearted (2007) claims that in order to assess the default risk, here is no experience that the hurt of house has reduced in the whole of America.However, the expense of house started to fall from the end of 2006 in lots of areas of America (Goodhearted, 2007). Because the rate of mortgage is less than the debts and the growing interest rate, increasingly sub-prime borrowers gave up re buckle undering currency to banks. Consequently, even though lenders had sold these mortgages, it cannot cover the loss. In other words, the income gained by selling houses was not enough to offset the measure outs of the credit and interest. As a result, these banks were suffering serious loss and some of them had to close down. 4 The join between Shoal article, agency theory and financial crisis In recent years, agency theory is widely used in lots of corporation and regarded it as the fundamental theory of corporate governance. Agency theory has contend an heavy role in handed-down control systems. Moreover, in this theory, shareholders use the method of supervision and reward to control mangers and employees. It is the arse of agency theory to maximize the protect of shareholders. Principals need to supervise agents whether they heighten on shareholder interest when they are operating a corporation.However, Shoal (2005) strongly points out hat this theory does not improve the companys performance, because it is analyse by physical science and indeed neglect the moral and ethic of human. Because the contrastive perspectives between shareholders and agents, they can make the various(a) terminations. Thus some primary issues should be focused on in agency theory. Firstly, because of the diverse goals between principals and agents, how to align them has become difficult (Lehman and Continue, 2013 1). Secondly, how to guarantee agents carry out fit to principals id eas. Lehman and Continue, 2013). Shareholders are interested in semipermanent strategies which can backable evolve their corporations. In other words, in semipermanent strategies, shareholders value, such as stock footing and dividends, can be maximized (Klein, 2009). In contrast, agents focus on miserable-term strategies so that they reject long-term strategies. In this way, they not only can efficaciously avoid unpredictable parking brake which usually occur in long-term strategies, but also can strike profit in a pathetic time. It is why leaders Just give way attention to currently profit and eclipse long-term development.For example, they whitethorn use lowly raw material to manufacture (Lehman and Continue, 2013 1). As a result, current margin can amplify however, they engender overlooked some more corporation. Obviously, the loss of long-term cannot be estimated. This is sympathetic as the sub-prime mortgage. Lenders prefer to lend currency to sub-prime borrowe rs, because of the higher interest rate. They can store more properties in a short time. In addition, if the housing scathe is higher than the price of mortgages, borrowers will try their go around to repay the debt, because they do not indigence to lose their house.To assume, if a mortgagor cannot well timed(p) repay, house, as a mortgage, will go bad to the bank. Namely, when the bank sale this house, it can narrow extra property immediately. In this case, bestow currency to borrowers, even though they are sub-prime borrowers, it is hardly to get damage to lenders. However, loaners set out only noticed the short-term profit, therefore, they loaned mortgage to sub-prime borrowers instead of prime borrowers however, they had neglected sustainable development, specially when the price of house dramatically declined.In fact, when the housing price decreased, some borrowers favored to give up the mortgage to lenders, especially the value of house is lower than the loans (Kl ein, 2009). In other words, banks only can grow these mortgages instead of the loans. As a result, colossal loss derived these banks collapse. Furthermore, mortgage lender also can resell theses mortgage to enthronisation bank. However, some of them had haze overd some information in order to a higher price (Klein, 2009). In this way, some drawback of mortgage cannot be known by a new buyer.What is worse, these shortcomings whitethorn be modified to become some advantages to attract others. This fraud and lemonlike practice had continuing occurred. Namely, there are increasingly investing companies were involved in this event. Nevertheless, because the housing price decreased, these mortgages had devalued, which caused a serious debt crisis. Shoal (2005) points out that business school should open some ethic courses to teach their students more accountable. Obviously, he has predicted this perspective.Initially, if lenders do not only pay attention to short-time strategies, the y did not only pursue the minimization of value in a short time and preferred to lend currency to prime borrowers rather than sub-prime borrowers. Even though the price of house decreased, borrowers are bound to consider their reedit, because they do not want to be classified in sub-prime borrowers. Additionally, they had stable Jobs to reassure the possible of repayment. Namely, banks whitethorn not systematically suffer such a gigantic blow.Furthermore, in order to earn greater profit, some agents had lent more than 20 times cash than the value the companys trade protection assets. Was (2010) convincingly points out that highly leveraged balance existed in some financial institutions. For example, investment banks liabilities-to-assets ratio was 0. 96 at the end of 2006 (Was, 2010). In other words, the majority of assert was borrowed. Even though these agents used insurance to communicate risk, blind pursuit of interests had brought some commodious hazard. Sometimes, if an a gent is indeed regarded as a selfish man, it will damage the do good of his or her corporation.Even though it may be reasonable that agent should some implicit in(p) differences between physical science and business studies. In other words, some theories which are correct in physical science cannot be reasonably used in business studies. Eisenhower (1989, citied in Lehman and Continue, 2013 1) points out that it is a significant issue that if an agent makes a decision, it will be fisticuff for principals to check whether this decision is beneficial for the company, such as creative accounting which is seriously harmful the profit of corporation.Furthermore, managers may not want to spend capital on long-term research and development, because it can compress the short-term interest (Lehman and Continue, 2013 2). Therefore, even though it seems exact that mangers should maximize the value of shareholders, Shoal discounts this view. He (200581) convincingly argues that this is the unrealistic assumptions and humans moral and ethic have been overlooked in this theory. In fact, shareholders and agents have the diverse goals, which meaner that shareholders are interested in long-term strategy oppositely, agents prefer to focus on the short-term strategy.Because of the unrealistic assumptions, agency jobs which contribute to the 2008 global financial crisis are ignored. 3 Implication in article 3. 1 Stewardship can remit financial crisis In Shoals article, he argues that stewardship theory which can be alliterative to flip-flop the agency theory can remit the problem between principals and agents (Shoal, 2005). Stewardship theory does not embolden face-to-face interest, but the elective profit. In this theory, collective profit is higher than the personal benefit.Hernandez (2008) points out that agents and shareholders benefit can be aligned in stewardship theory. Responsibility and psychological ownership are combined with the profit of shareholders (Block, 1996 Davis, Chairman, and Donaldson 1997 citied in Spheres et al, 20122). In other words, they have become a collective and the interests of collective have intimately linked with personal profits. According to Hernandez (2008), employees can feel more responsible and effectuate their obligations in stewardship theory.Because the interest has become consistent, the at odds(p) goals may not exist. Compared with agency theory which monitoring is necessary between shareholders and agents, shareholders and supply can cooperate in a harmonious environment. Furthermore, stewardship is also beneficial for realizing the interactions between sales personnel and consumers (De Router, De Gong and Wetness 2009 Hernandez, 2008, citied in Spheres et al, 2012). Therefore, it is good for a corporation to pay attention to customers, staff and shareholders simultaneously.Take sub-prime crisis makes an assumption, if the majority of corporation judge he stewardship theory instead of the agency th eory before the 2008 global financial crisis, the credit tsunami might not occur or it was not as heavy as this. Interest among agents, shareholders and customers are tightly relevant. In other words, agents and shareholders may not only focus on the short-term profit and ignore long- place. Therefore, they may prefer to lend currency for prime borrowers while limit the amount of loans which is loaned to sub-prime borrowers.In addition, when lenders resell their mortgage, they may not deliberately hide weak information and ay not qualify shortcomings in order to resell a higher price. Even though the agency theory has been extensively used in the world, Shoal has realized the drawback of it and try to replace it. The agency theory has contributed to the 2008 global financial crisis to a large degree. Namely, Shoal has forecasted the issue which has widely existed in the majority of companies. Furthermore, the stewardship theory advocated by Shoal can effectively remit the problems between shareholders and agents.It also can decrease the harm brought by financial crisis to some extent. 4 practice relevance 4. The power of government While it can effectively decrease the probability of financial crisis that using the stewardship theory replaces the agency theory, it is not enough. Therefore, the power of government cannot be overlooked. Because it can cause frugal bubble that a government continually slash interest rates or dramatically reduce interest rates. However, American government had incessantly reduced the interest rate xiii times from 2001 to 2003.As a result, it caused the boom of American real estate. In addition, the application setting of sub-prime mortgage had decreased. A large umber of people preferred to purchase a house in installment plan, which caused the 2008 global financial crisis. Therefore, except for the stewardship theory, government also should pay attention to the frequency and the flow of decreasing rate. Excessively fast dec line the interest rate or outsize decrease them may cause economic bubble, which can harm for the domestic financial market.What is worse, it can lead to global economic crisis. Thus improper regulations may validatory lead to financial crisis. In addition, it is important that government should limit the rate of the sub-prime mortgage in any investment bank. Klein (2009) points out that regulation which can defend financial marker should be built by government. In other words, reasonable legislative can effectively prevent financial crisis. Consequently, the effect of government cannot be ignored. It also can effectually protect financial market and prevent huge loss.While the preponderant economic system is free marker, political macro-control, which is beneficial to the current economic system, is inevitable. 5 Conclusion Agency theory has described the relationship between principals and agents. Even Hough the universe of the agency theory is to maximize the value of shareho lder, Shoal (2005 81) convincingly points out that it is falsely built on an unrealistic crisis. Because sub-prime borrowers have the lower credit and lower repayment ability, when the value of mortgage was less than the loan, they preferred to give up repaying the debt.As a result, sub-prime lenders had to sustain the huge loss. However, agents only focused on the short-term profit. They preferred to loan currency to sub-prime borrowers. Therefore, borrowing currency to sub-prime borrowers had become a common phenomenon in that period. Even though Shoals article was published before the worldwide financial crisis, he was still advised of the problems of agency theory in economic system. While agency theory is accepted by the majority of corporations, it still has some serious problems.